Congenital horizontal gaze palsy and kyphoscoliosis in two brothers.

Congenital horizontal gaze palsy and kyphoscoliosis in two brothers.

In a sibship of 11, two brothers with a congenital complete horizontal gaze palsy developed severe kyphoscoliosis. No-one else in the family has a gaze palsy or comparable skeletal abnormalities. Since the parents are first cousins, an autosomal recessive mode of inheritance seems likely.

Congenital horizontal gaze palsy and kyphoscoliosis.

Horizontal Gaze Palsy: Additional Issues

I read with interest the article by Gautam, et al. [1]. I agree that brainstem tuberculoma can cause nuclear gaze palsy and fascinating neuro-ophthalmological findings. However, I think further clarification regarding pathophysiological mechanism of the gaze palsy may be interesting for the readers. Particularly, two points I want to raise are: difficulty in differentiating pathological lesions...

Isolated Horizontal Gaze Palsy: Observations and Explanations

We present three cases that we suggest require a novel diagnosis and a reconsideration of current understandings of pontine anatomy. In this case series, we highlight a series of patients with monophasic, fully recovering inflammatory lesions in the pontine tegmentum not due to any of the currently recognized causes of this syndrome. We highlight other similar cases in the literature and sugges...

Congenital leukonychia totalis in two brothers.

Sir, was no known consanguinity in the reported family. For this Leukonychia, or white nails, is a common finding in nails of reason, the occurrence of white nails in the two brothers seems fingers or toes (1). It is a very heterogeneous condition, with to be an autosomal recessive segregation. There is only one many different causes. In a recent review, Grossmann & Scher case to our knowledge ...